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Year : 2020  |  Volume : 40  |  Issue : 2  |  Page : 99-105

Assessment of depression and anxiety in relation to quality of life in patients with vitiligo

1 Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Assiut University, Assiut, Egypt
2 Department of Neurology and Psychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt
3 Department of Dermatology and Andrology, Mental Health Hospital, Assiut, Egypt

Correspondence Address:
Dr. Doaa S Sayed
Associate Professor of Dermatology, Venereology and Andrology, Assiut University
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ejdv.ejdv_54_19

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Background Vitiligo is a common skin disease that has been reported to affect ∼1% of the population worldwide. Many patients with vitiligo feel distressed and stigmatized by their condition. Objective The aim was to assess the effect of vitiligo on the patients’ quality of life and to ascertain comorbidity of depression and anxiety associated with the disease using Hamilton rating scale for anxiety and depression. Patients and methods One hundred patients with vitiligo and 50 control participants were subjected to clinical examination with assessment of vitiligo severity by vitiligo area scoring index (VASI) in addition to their assessment by dermatology life quality index (DLQI), Hamilton depression rating scale, and Hamilton anxiety rating scale. Results In this study, there was a significantly higher DLQI score among the study group compared with controls (P<0.001). Moreover, there was a highly significant difference in the Hamilton depression score (P<0.001) between the study group (24±7) and control group (3.8±1.6). Moreover, the study group scored higher on the Hamilton anxiety scale in comparison with the control groups, and this difference was statistically significant (P<0.001). A significant positive correlation was found between VASI score and both DLQI and Hamilton depression score (r=0.41 and 0.33, respectively). These correlations were statistically significant (P<0.001). Moreover, there was a significant positive correlation between VASI score and Hamilton anxiety score (r=0.20, P=0.022). Conclusion Vitiligo has a negative effect on patient’s psychological status in terms of anxiety and depression, especially in female patients, patients with increased body surface involvement, and those with lesions on exposed parts of the body.

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